Serveur d'exploration sur la grippe en Espagne

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Estimating influenza vaccine effectiveness in Spain using sentinel surveillance data.

Identifieur interne : 000181 ( Main/Exploration ); précédent : 000180; suivant : 000182

Estimating influenza vaccine effectiveness in Spain using sentinel surveillance data.

Auteurs : S. Jimenez-Jorge [Espagne] ; S. De Mateo ; C. Delgado-Sanz ; F. Pozo ; I. Casas ; M. Garcia-Cenoz ; J. Castilla ; C. Rodriguez ; T. Vega ; C. Quinones ; E. Martinez ; J M Vanrell ; J. Gimenez ; D. Castrillejo ; J M Altzibar ; F. Carril ; J M Ramos ; M C Serrano ; A. Martinez ; N. Torner ; E. Perez ; V. Gallardo ; A. Larrauri

Source :

RBID : pubmed:26212144

Descripteurs français

English descriptors

Abstract

We aimed to estimate influenza vaccine effectiveness (VE) against laboratory-confirmed influenza during three influenza seasons (2010/11 to 2012/2013) in Spain using surveillance data and to compare the results with data obtained by the cycEVA study, the Spanish component of the Influenza Monitoring Vaccine Effectiveness (I-MOVE) network. We used the test-negative case–control design, with data from the Spanish Influenza Sentinel Surveillance System (SISS) or from the cycEVA study. Cases were laboratory-confirmed influenza patients with the predominant influenza virus of each season, and controls were those testing negative for any influenza virus. We calculated the overall and age-specific adjusted VE. Although the number of patients recorded in the SISS was three times higher than that in the cycEVA study, the quality of information for important variables, i.e. vaccination status and laboratory results, was high in both studies. Overall, the SISS and cycEVA influenza VE estimates were largely similar during the study period. For elderly patients (> 59 years), the SISS estimates were slightly lower than those of cycEVA, and estimates for children (0–14 years) were higher using SISS in two of the three seasons studied. Enhancing the SISS by collecting the date of influenza vaccination and reducing the percentage of patients with incomplete information would optimise the system to provide reliable annual influenza VE estimates to guide influenza vaccination policies.

DOI: 10.2807/1560-7917.es2015.20.28.21187
PubMed: 26212144


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">We aimed to estimate influenza vaccine effectiveness (VE) against laboratory-confirmed influenza during three influenza seasons (2010/11 to 2012/2013) in Spain using surveillance data and to compare the results with data obtained by the cycEVA study, the Spanish component of the Influenza Monitoring Vaccine Effectiveness (I-MOVE) network. We used the test-negative case–control design, with data from the Spanish Influenza Sentinel Surveillance System (SISS) or from the cycEVA study. Cases were laboratory-confirmed influenza patients with the predominant influenza virus of each season, and controls were those testing negative for any influenza virus. We calculated the overall and age-specific adjusted VE. Although the number of patients recorded in the SISS was three times higher than that in the cycEVA study, the quality of information for important variables, i.e. vaccination status and laboratory results, was high in both studies. Overall, the SISS and cycEVA influenza VE estimates were largely similar during the study period. For elderly patients (> 59 years), the SISS estimates were slightly lower than those of cycEVA, and estimates for children (0–14 years) were higher using SISS in two of the three seasons studied. Enhancing the SISS by collecting the date of influenza vaccination and reducing the percentage of patients with incomplete information would optimise the system to provide reliable annual influenza VE estimates to guide influenza vaccination policies.</div>
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<AbstractText>We aimed to estimate influenza vaccine effectiveness (VE) against laboratory-confirmed influenza during three influenza seasons (2010/11 to 2012/2013) in Spain using surveillance data and to compare the results with data obtained by the cycEVA study, the Spanish component of the Influenza Monitoring Vaccine Effectiveness (I-MOVE) network. We used the test-negative case–control design, with data from the Spanish Influenza Sentinel Surveillance System (SISS) or from the cycEVA study. Cases were laboratory-confirmed influenza patients with the predominant influenza virus of each season, and controls were those testing negative for any influenza virus. We calculated the overall and age-specific adjusted VE. Although the number of patients recorded in the SISS was three times higher than that in the cycEVA study, the quality of information for important variables, i.e. vaccination status and laboratory results, was high in both studies. Overall, the SISS and cycEVA influenza VE estimates were largely similar during the study period. For elderly patients (> 59 years), the SISS estimates were slightly lower than those of cycEVA, and estimates for children (0–14 years) were higher using SISS in two of the three seasons studied. Enhancing the SISS by collecting the date of influenza vaccination and reducing the percentage of patients with incomplete information would optimise the system to provide reliable annual influenza VE estimates to guide influenza vaccination policies.</AbstractText>
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<Author ValidYN="Y">
<LastName>Larrauri</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
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<CollectiveName>Spanish Influenza Sentinel Surveillance System</CollectiveName>
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<ArticleDate DateType="Electronic">
<Year>2015</Year>
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<Country>Sweden</Country>
<MedlineTA>Euro Surveill</MedlineTA>
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<MeshHeading>
<DescriptorName UI="D007252" MajorTopicYN="N">Influenza Vaccines</DescriptorName>
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</MeshHeading>
<MeshHeading>
<DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
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<DescriptorName UI="D018571" MajorTopicYN="Y">Sentinel Surveillance</DescriptorName>
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<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
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<Month>7</Month>
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<ArticleId IdType="doi">10.2807/1560-7917.es2015.20.28.21187</ArticleId>
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<li>Espagne</li>
</country>
<region>
<li>Communauté de Madrid</li>
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<li>Madrid</li>
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<name sortKey="Casas, I" sort="Casas, I" uniqKey="Casas I" first="I" last="Casas">I. Casas</name>
<name sortKey="Castilla, J" sort="Castilla, J" uniqKey="Castilla J" first="J" last="Castilla">J. Castilla</name>
<name sortKey="Castrillejo, D" sort="Castrillejo, D" uniqKey="Castrillejo D" first="D" last="Castrillejo">D. Castrillejo</name>
<name sortKey="De Mateo, S" sort="De Mateo, S" uniqKey="De Mateo S" first="S" last="De Mateo">S. De Mateo</name>
<name sortKey="Delgado Sanz, C" sort="Delgado Sanz, C" uniqKey="Delgado Sanz C" first="C" last="Delgado-Sanz">C. Delgado-Sanz</name>
<name sortKey="Gallardo, V" sort="Gallardo, V" uniqKey="Gallardo V" first="V" last="Gallardo">V. Gallardo</name>
<name sortKey="Garcia Cenoz, M" sort="Garcia Cenoz, M" uniqKey="Garcia Cenoz M" first="M" last="Garcia-Cenoz">M. Garcia-Cenoz</name>
<name sortKey="Gimenez, J" sort="Gimenez, J" uniqKey="Gimenez J" first="J" last="Gimenez">J. Gimenez</name>
<name sortKey="Larrauri, A" sort="Larrauri, A" uniqKey="Larrauri A" first="A" last="Larrauri">A. Larrauri</name>
<name sortKey="Martinez, A" sort="Martinez, A" uniqKey="Martinez A" first="A" last="Martinez">A. Martinez</name>
<name sortKey="Martinez, E" sort="Martinez, E" uniqKey="Martinez E" first="E" last="Martinez">E. Martinez</name>
<name sortKey="Perez, E" sort="Perez, E" uniqKey="Perez E" first="E" last="Perez">E. Perez</name>
<name sortKey="Pozo, F" sort="Pozo, F" uniqKey="Pozo F" first="F" last="Pozo">F. Pozo</name>
<name sortKey="Quinones, C" sort="Quinones, C" uniqKey="Quinones C" first="C" last="Quinones">C. Quinones</name>
<name sortKey="Ramos, J M" sort="Ramos, J M" uniqKey="Ramos J" first="J M" last="Ramos">J M Ramos</name>
<name sortKey="Rodriguez, C" sort="Rodriguez, C" uniqKey="Rodriguez C" first="C" last="Rodriguez">C. Rodriguez</name>
<name sortKey="Serrano, M C" sort="Serrano, M C" uniqKey="Serrano M" first="M C" last="Serrano">M C Serrano</name>
<name sortKey="Torner, N" sort="Torner, N" uniqKey="Torner N" first="N" last="Torner">N. Torner</name>
<name sortKey="Vanrell, J M" sort="Vanrell, J M" uniqKey="Vanrell J" first="J M" last="Vanrell">J M Vanrell</name>
<name sortKey="Vega, T" sort="Vega, T" uniqKey="Vega T" first="T" last="Vega">T. Vega</name>
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<country name="Espagne">
<region name="Communauté de Madrid">
<name sortKey="Jimenez Jorge, S" sort="Jimenez Jorge, S" uniqKey="Jimenez Jorge S" first="S" last="Jimenez-Jorge">S. Jimenez-Jorge</name>
</region>
</country>
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